Publications

Jia S, Ratzan EM, Goodrich EJ, Abrar R, Heiland L, Tarchini B, Deans MR. Elife. 2023 May 5;12:e84910. doi: 10.7554/eLife.84910. Online ahead of print.
PMID: 37144879 |DOI: 10.7554/eLife.84910

Kale S, Williams ME, Deans MR. Getting connected: Pathfinding anf synaptogenesis in neural development, evolution, and disease. Dev Dyn. 2023 Jan;252(1):7-9. doi: 10.1002/dvdy.558.
PMID: 36591889 |DOI: doi: 10.1002/dvdy.558

Deans MR. Planar cell polarity signaling guides cochlear innervation. Dev Biol. 2022 Mar 17;486:1-4.
PMID: 35306005 |DOI: doi: 10.1016/j.ydbio.2022.03.005

Avilés EC, Krol A, Henle SJ, Burroughs-Garcia J, Deans MR, Goodrich LV. Fat3 acts through independent cytoskeletal effectors to coordinate asymmetric cell behaviors during polarized circuit assembly. Cell Rep. 2022 Feb;38(5):110307.
PMID: 35108541 |DOI: 10.1016/j.celrep.2022.110307

Simon F, Tissir F, Michel V, Lahlou G, Deans MR, Beraneck M. Implication of Vestibular Hair Cell Loss of Planar Polarity for the Canal and Otolith-Dependent Vestibulo-Ocular Reflexes in Celsr1 -/- Mice. Frontiers in Neuroscience . 2021 Nov 11;15:750596.
PMID: 34790090 |DOI: 10.3389/fnins.2021.750596

Deans MR. Conserved and Divergent Principles of Planar Polarity Revealed by Hair Cell Development and Function. Frontiers in Neuroscience. 2021 Oct 18;15:742391.
PMID: 34733133 |DOI: 10.3389/fnins.2021.742391

Ratzan EM, Moon AM, Deans MR. Fgf8 genetic labeling reveals the early specification of vestibular hair cell type in mouse utricle. Development. 2020 Nov 19;147(22):dev192849.
PMID: 33046506 |DOI: 10.1242/dev.192849

Almishaal A, Mathurn PD, Franklin L, Shi K, Haller T, Martinovic A, Hirschmugl K, Earl BR, Zhang C, Yang J, Deans MR, Firpo M, Park AH. “Role of Cochlear Synaptopathy in Cytomegalovirus Infected Mice and in Children”. International Journal of Pediatric Otorhinolaryngology. 2020 Aug 4;138:110275.
PMID: 32828018 | DOI: 10.1016/j.ijporl.2020.110275

Derish I, Lee J, Wong-King-Cheong M, Babayeva S, Caplan J, Leung V, Shahinian C, Gravel M, Deans MR, Gros P, Torban E. “Differential Role of Planar Cell Polarity Gene Vangl2 in Embryonic and Adult Mammalian Kidneys”. PLoS ONE. 2020 Mar 23;15(3):e0230586.
PMID: 32203543 | DOI: 10.1371/journal.pone.0230586

Ghimire SR, Deans MR. “Frizzled3 and Frizzled6 Cooperate with Vangl2 to Direct Cochlear Innervation by type II Spiral Ganglion Neurons”. J. Neuroscience. 2019 Oct 9;39(41):8013-8023.
PMID: 31462532 |DOI: 10.1523/JNEUROSCI.1740-19.2019

Duncan JS, Fritzsch B, Houston DW, Ketchum EM, Kersigo J, Deans MR, Elliott KL. “Topologically correct central projections of tetrapod inner ear afferents require Fzd3 “. Scientific Reports 2019 July16;9(1):10298.
PMID: 31311957 |DOI: 10.1038/s41598-019-46553-6

Ghimire SR, Ratzan EM, Deans MR. “A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea”. Development 2018 June 14;145(12).
PMID: 29784671 |DOI: 10.1242/dev.159012

Stoller ML, Roman OR, Deans MR. "Domineering Non-Autonomy in Vangl1;Vangl2 Double Mutants Demonstrates Intercellular PCP Signaling in the Vertebrate Inner Ear". Developmental Biology 2018 May 1;437(1):17-26. doi: 10.1016/j.ydbio.2018.02.021.
PMID: 2951011|DOI: 10.1016/j.ydbio.2018.02.021

Goodyear R, Lu X, Deans MR, Richardson R. “A Tectorin-Based Matrix and Planar-Cell-Polarity Genes are Required for Normal Collagen-Fibril Orientation in the Developing Tectorial Membrane”. Development 2017 Nov 1;144(21):3978-3989.
PMID: 28935705 |DOI: 10.1242/dev.151696

Cetera M, Leybova L, Woo FW, Deans MR, Devenport D. “Planar cell polarity-dependent and independent functions in the emergence of tissue-scale hair follicle patterns”. Developmental Biology 2017 Aug 1;428(1):188-203.
PMID: 28599846|DOI: 10.1016/j.ydbio.2017.06.003

Duncan JS, Stoller ML, Francl AF, Tissir F, Devenport D, Deans MR. "Celsr1 Coordinates the Planar Polarity of Vestibular Hair Cells During Inner Ear Development". Developmental Biology 2017, March 15; 423(2):126–137.
PMID: 28159525 |DOI: 10.1016/j.ydbio.2017.01.020

Cheng H, Burroughs-Garcia J, Birkness JE, Trinidad JC, Deans MR. "Disparate Regulatory Mechanisms Control Fat3 and P75NTR Protein Transport Through a Conserved Kif5-Interaction Domain". PLoS ONE 2016, Oct 27;11(10):e0165519.
PMID: 27788242 |DOI: 10.1371/journal.pone.0165519

Simmons AB, Merrill MM, Reed JC, Deans MR, Edwards MM, Fuerst PG. “Defective angiogenesis and intraretinal bleeding in mouse models with disrupted inner retinal lamination”. IOVS 2016, April;57:1563-1577.
PMID: 27046121 |DOI: 10.1167/iovs.15-18395

May-Simera HL, Petralia RS, Montcouquiol M, Wang YX, Szarama KB, Liu Y, Lin W, Deans MR, Pazour GJ, Kelley MW. “Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea.” Development 2015, Feb 1;142(3):555-66.
PMID: 25605782 |DOI: 10.1242/dev.113696

Copley CO, Duncan JS, Liu C, Cheng H, Deans MR. “Postnatal Refinement of Auditory Hair Cell Planar Polarity Deficits Occurs in the Absence of Vangl2.” Journal of Neuroscience 2013, Aug 28; 33(35):14001-14016.
PMID: 23986237 |DOI: 10.1523/JNEUROSCI.1307-13.2013

Deans MR. “A Balance of Form and Function: Planar Polarity in Development of the Vestibular Maculae.” Seminars in Cell & Developmental Biology 2013, May 24(5):490-8.
PMID: 23507521 |DOI: 10.1016/j.semcdb.2013.03.001

Yin H, Copley CO, Goodrich LV, Deans MR. “Comparison of Phenotypes between Different vangl2 Mutants Demonstrates Dominant Effects of the Looptail Mutation during Hair Cell Development.” PLoS ONE Feb 20, 2012, PMCID: PMC3282788.
PMID: 22363783 |DOI: 10.1371/journal.pone.0031988

Deans MR, Krol A, Abraira VE, Copley CO, Tucker AF, Goodrich LV. “Control of Neuronal Morphology by the Atypical Cadherin Fat3.” Neuron 2011 Sep 8;71(5):820-32, PMCID: PMC3521586 .
PMID: 21903076 |DOI: 10.1016/j.neuron.2011.06.026

Deans MR, Peterson JM, and Wong GW. “Mammalian Otolin: A Multimeric Glycoprotein Specific to the Inner Ear that Interacts with Otoconial Matrix Protein Otoconin-90 and Cerebellin-1.” PLoS ONE Sept 2010; 5(9), PMCID: PMC2939893.
PMID: 20856818 |DOI: 10.1371/journal.pone.0012765

Deans MR, Antic D, Suyama K, Scott MP, Axelrod JD, Goodrich LV. “Asymmetric Distribution of Prickle-like 2 Reveals an Early Underlying Polarization of Vestibular Sensory Epithelia in the Inner Ear.” Journal of Neuroscience 2007 Mar 21; 27(12):3139-47 ..
PMID: 17376975 |DOI: 10.1523/JNEUROSCI.5151-06.2007

Kosaka T, Deans MR, Paul DL, Kosaka K. “Neuronal Gap Junctions in the Mouse Main Olfactory Bulb: Morphological Analyses on Transgenic Mice” Neuroscience 2005; 134(3):757-69.
PMID: 15979807|DOI: 10.1016/j.neuroscience.2005.04.057

Volgyi B, Deans MR, Paul DL, Bloomfield SA. “Convergence and Segregation of the Multiple Rod Pathways in Mammalian Retina.” Journal of Neuroscience 2004 Dec 8; 24(49): 11182-11192, PMCID: PMC2834589.
PMID: 15590935 |DOI: 10.1523/JNEUROSCI.3096-04.2004

Long MA, Deans MR, Paul DL, Connors BW. “Rhythmicity without Synchrony in the Electrically Uncoupled Inferior Olive.” Journal of Neuroscience 2002 Dec 15; 22(24):10898-905, PMCID: PMC2834587.
PMID: 12486184 |DOI: 10.1523/JNEUROSCI.22-24-10898.2002

Deans MR, Volgyi B, Goodenough DA, Bloomfield SA, Paul DL. “Connexin36 is Essential for Transmission of Rod-Mediated Visual Signals in the Mammalian Retina.” Neuron 2002 Nov 14; 36(4):703-712, PMCID: PMC2834592.
PMID: 12441058 |DOI: 10.1016/s0896-6273(02)01046-2

Deans MR and Paul DL. “Mouse horizontal cells do not express connexin26 or connexin36.” Cell Communication and Adhesion 2002; 8(4-6):361-6, PMCID: PMC2834531.
PMID: 12064619 |DOI: 10.3109/15419060109080754

Landisman CE, Long MA, Beierlein M, Deans MR, Paul DL, Connors BW. “Electrical synapses in the thalamic reticular nucleus.” Journal of Neuroscience 2002 Feb 1; 22(3):1002-9.
PMID: 11826128 |DOI: 10.1523/JNEUROSCI.22-03-01002.2002

Deans MR, Gibson JR, Sellitto C, Connors BW, Paul DL. “Synchronous Activity of Inhibitory Networks in Neocortex Requires Electrical Synapses Containing Connexin36.” Neuron 2001 Aug 16; 31(3):477-85.
PMID: 11516403 |DOI: 10.1016/s0896-6273(01)00373-7

White TW, Deans MR, O'Brien J, Al-Ubaidi MR, Goodenough DA, Ripps H, Bruzzone R. “Functional Characteristics of Skate Connexin35, a Member of the Gamma Subfamily of Connexins Expressed in the Vertebrate Retina.” European Journal of Neuroscience 1999 June; 11(6):1883-90.
PMID: 10336656 |DOI: 10.1046/j.1460-9568.1999.00607.x

White TW, Deans MR, Kelsell DP, Paul DL. “Connexin mutations in deafness.” Nature 1998 Aug 13; 394(6694):630-1.
PMID: 9716127 |DOI: 10.1038/29202